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104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft 2006

Abstract
Abstract

SO.05.04

Severe aspergillus endophthalmitis occurring after liver transplantation in an 8-month-old baby

Pollack K.1, Naeke A.2, Fischer R.3, Kohlhaas M.1, Pillunat L. E.1
1Eye Clinic, Technical University Dresden; 2Child Hospital, Technical University Dresden; 3Institut of Pathology, Technical University Dresden

Objective: Immunosuppressed patients and patients transplants bear an increased risk to invasive aspergillosis and aspergillus endophthalmitis.
Aspergillus endophthalmitis is caused by direct invasion via chorioidal and retinal blood vessels. An early diagnosis of this condition by bedside fundoscopic examination.is important in morder to prevent death of disseminated Aspergillus infection .
Methods: A 8-month-old boy with primary biliary liver cirrhosis underwent liver transplantation. Three days later an unilateral panuveitis was observed. Despite of systemic antibiotic and fungicidal therapy his condition worsened, with purulent material being found in the anterior chamber.
The eye was enucleated. Our findings are illustrated in the clinical photographs and histopathological pictures.
Results: The histopathological examination showed a severe Aspergillus endophthalmitis with extensive necrosis and masses of fungal filaments.
Conclusions: The Aspergillus endophthalmitis is an important complication after liver transplantation. In severe cases, an enucleation is necessary in order to prevent a life threatening disseminated Aspergillus infection.


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