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104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft 2006
Abstract
Abstract
FR.01.13 Comparison of central corneal thickness measurements by Stratus-OCT, ultrasound pachymetry and Orbscan II in normal and glaucoma eyes Pache M., Planert A., Kube T., Funk J.
Augenklinik, Universitätsklinikum Freiburg Objective: We evaluated the capability of the Stratus-OCT to assess central corneal thickness (CCT) in normals and glaucoma patients and compared the method with ultrasound pachymetry (UP) and Orbscan II.
Methods: We prospectively assessed CCT in 200 eyes of 100 subjects (50 normals, 35 POAG, 9 NTG, 6 OHT patients) in randomized order. We compared the results of 3 measurements by Stratus-OCT and Orbscan II and 5 measurements by UP with respect to mean value, SD, eye symmetry, reproducibility, and level of agreement between the 3 methods.
Results: Mean CCT values where highest by UP (555±37 µm for right eyes, 560±37 µm for left eyes), followed by Stratus-OCT (549±36 µm for right eyes, 550±37 µm for left eyes) and Orbscan II (536±41 µm for right eyes, 537±41 µm for left eyes). The difference between right and left eyes was significant for UP. Intraclass correlation coefficient Kappa was 0.99 for UP and Stratus-OCT and 0.98 for Orbscan II. Bland-Altman analysis demonstrated a higher level of agreement between Stratus-OCT and UP than between Orbscan II and Stratus-OCT or between Orbscan II and UP. Patients with NTG showed the lowest, patients with OHT the highest CCT.
Conclusions: The Stratus-OCT allows highly reproducible non-contact assessment of CCT with a high level of agreement with UP. The symmetry between both eyes was even higher with this method. In agreement with previous studies, NTG patients showed a lower, OHT patients a higher CCT than normals.
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