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104. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft 2006
Abstract
Abstract
DO.13.07 Clinicopathologic concepts in age-related orbital disease Meiller R., Papadopoulos T., Kruse F. E., Holbach L. M.
Department of Ophthalmology and Eye Hospital and Department of Pathology, University Erlangen-Nürnberg, Erlangen Objective: To determine clinicopathologic features of orbital disease in relation to the patient’s age.
Methods: Review of clinical records of 223 consecutive patients with orbital lesions, excisional or incisional biopsy using anterior or lateral orbitotomy and presentation of clincopathologic features in relation to the patientÂ’s age.
Results: The most common lesions in adults were: 1. lymphoid tumors (lymphoid hyperplasia, Non-Hodgkin-lymphoma, plasmocytoma) 2. vascular lesions (cavernous hemangioma, intraosseous cavernous hemangioma, hemangiopericytoma, lymphangioma, varix, angiosarcoma) 3. inflammatory lesions (pseudotumor, WegenerÂ’s granulomatosis, paraffin granuloma, foreign body granuloma, sarcoid, xanthogranuloma, infectious staphylococci-associated orbital cellulitis, silent-sinus-syndrome, cholesterol granuloma) 4. lacrimal gland tumors (pleomorphic adenomas, dacryops, adenoid-cystic carcinoma) 5. metastases. The most common lesions in childhood were: 1. cysts (dermoid cysts, conjunctival dermoids, epithelial implantation cysts, microphthalmos with colobomatous orbital cyst) 2. rhabdomyosarcoma 3. hemangioma 4. lymphangioma. Practical examples of clinicopathologic correlations are presented.
Conclusions: Age is an important factor in the differential diagnosis of orbital disease. Clinicopathologic correlations improve the understanding of orbital disease and are important for diagnosis and management.
Supported by Sander – Stiftung
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